Lecture 10 Linkage Analysis February

نویسندگان

  • Elizabeth Thompson
  • Brendan Mumey
چکیده

Although the title of this lecture is “linkage analysis” it is going to be mostly about computing probabilities. Linkage analysis can be performed for a variety of species. We will concentrate on the case where the individuals in the pedigree are humans. Human pedigrees present some unique problems in that the data is often incomplete. In particular some individuals may be unobserved, or the trait genotypes and possibly the phase of homologous pairs may be unknown.

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تاریخ انتشار 1996